Corneal Penetration of Polyhexamethylene Biguanide and Chlorhexidine Digluconate
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چکیده
منابع مشابه
Maximum Inhibitory Dilution of Mouthwashes Containing Chlorhexidine and Polyhexamethylene Biguanide against Salivary Staphylococcus Aureus
OBJECTIVE The aim of the present study was to determine the in vitro maximum inhibitory dilution (MID) of two chlorhexidinebased oral mouthwashes (CHX): Noplak, Periogard, and one polyhexamethylene biguanide-based mouthwash (PHMB): Sanifill Premium against 28 field Staphylococcus aureus strains using the agar dilution method. MATERIALS AND METHODS For each product, decimal dilutions ranging f...
متن کاملAntimicrobial efficacy of 3 oral antiseptics containing octenidine, polyhexamethylene biguanide, or Citroxx: can chlorhexidine be replaced?
BACKGROUND Use of oral antiseptics decreases the bacterial load in the oral cavity. OBJECTIVE To compare the antimicrobial activity of 3 novel oral antiseptics with that of chlorhexidine, which is considered the "gold standard" of oral hygiene. DESIGN Comparative in vitro study. METHODS Four common oral microorganisms (Streptococcus sanguinis, Streptococcus mutans, Candida albicans, and F...
متن کاملBenefit of polyhexamethylene biguanide in Fusarium keratitis.
PURPOSE To report a series of 3 patients with soft contact lens-related Fusarium keratitis. Two of them were treated with the antiamoebic polyhexamethylene biguanide 0.02% (PHMB) in combination with antifungal drugs, and 1 patient was treated with PHMB as sole antifungal regimen. METHODS Chart review of 3 patients treated with PHMB in Fusarium keratitis. Two of them were refractory to the com...
متن کاملEvaluating a dressing impregnated with polyhexamethylene biguanide
Aims: To evaluate a new polyhexamethylene biguanide (PHMB) foam dressing for inclusion in the specialist dressing section of a trust’s wound management formulary. Methods: KendallTM AMD (Covidien) antimicrobial foam dressing’s use was reviewed through a retrospective evaluation of patients who had been treated with the dressing. Data was collected from the medical and nursing notes of 25 patien...
متن کاملAntimicrobial action of biguanides on the viability of Acanthamoeba cysts and assessment of cell toxicity.
PURPOSE To assess dose- and concentration-dependent rates of biguanides on the viability of Acanthamoeba cysts isolated from severe ulcerative keratitis, and to correlate cysticidal activites with cytotoxic profiles in corneal and endothelial cells. METHODS Cysticidal activities of polyhexamethylene biguanide and chlorhexidine digluconate were evaluated in the Acanthamoeba castellanii strain ...
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ژورنال
عنوان ژورنال: Journal of Clinical & Experimental Ophthalmology
سال: 2015
ISSN: 2155-9570
DOI: 10.4172/2155-9570.1000430